The Impact off the address was major and in many ways Washington's words were still applicable well into the 20th century and even today.
Washington did not necessarily forbid America from a political party system but when the focus of said parties strayed away from the advancement of the United States of America we would be lost. In a way this says that until the very populace of America, the supporters of political parties no longer cared for their country and only sought personal gain.
Wars in Europe
America managed to stay away from the warmongering countries of Europe growing to be the country that could challenge the powers of Europe. The US was isolationist towards Europe until Cuba began to have problems with their colonial masters the Spanish this war that would come with Spain showed the great nations of Europe that the US was indeed a superpower. The US still managed to not be involved in a multi-country conflict until World War 1 in which we were a well developed superpower changing the pace of the war with our entrance on the battlefield.
There have been many different scandals throughout the US history some involving both presidents and their cabinet members and there are many corrupt scandals going on in american politics at all times. One such instance of Cabinet corruption was the Teapot Dome Scandal in which the Secretary of the Interior illegally leased the Teapot Dome fields to an oil company and a field in California to another person.